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Error Description: System.Net.WebException: The HTTP request is unauthorized with client authentication scheme 'Anonymous' error during integration with Biztalk

We are trying to integrate BIz talk with Salesforce. From Biz talk, Consumer Key and Consumer Secret is used to connect to Salesforce sandbox. It was working one month. Now we are getting error message as 
Error Description: System.Net.WebException: The HTTP request is unauthorized with client authentication scheme 'Anonymous'. The authentication header received from the server was 'Token'.
<?xml version="1.0" encoding="UTF-8"?><Errors><Error><errorCode>INVALID_SESSION_ID</errorCode><message>Session expired or invalid</message></Error></Errors>

Can you anyone help what is the problem. Is there any settings got updated in sandbox.