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Opportunity Line items and pricebooks

Two question:


1) Can we remove the pricebooks completely from SFDC? I have a requirement that the price of product will change on Demand and Supply and there is no fix price. 


2) Can we modify the add products wizard on Opportunity Line items? I want to add the shipment charges as well for all the products and wish to add it to the wizard when the product is added.


Is it possible using VF page? If yes, have anyone worked on something like this before and can share the algorithm or code snippet or a pseudo code.