I have a simple Apex Trigger to pass data to an external system, and I'm wondering if it is possible to add a filter criteria to exclude updates made by a specific user account?

Trigger eOne_SC_RTDS_Opportunity_U on Opportunity (after update) {
set<ID> ids = Trigger.newMap.keyset(); 
eOne_SC_RTDS.Process('Opportunity','update',ids); 
}